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Brain Lesions Are Most Often Reversible in Acute Thrombotic Thrombocytopenic Purpura Neurol 73:66-70, Burrus,T.M.,et al, 2009 See this aricle in Pubmed Article Abstract Posterior reversible encephalopathy syndrome is the most common brain imaging abnormality in severe manifestations of thrombotic thrombocytopenic purpura. Large infarctions and hemorrhage are infrequent. Consequently, abnormal brain neuroimaging does not seem to impact patient outcome, and full neurologic recovery is possible even in comatose patients with extensive brain abnormalities on MRI.

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